NRF2 co-opts the SWI/SNF complex to drive liver cell plasticity
Athena Jessica S. Ong, Chapman CH Wong, Anthony P. Karamalakis, Kimberley Jane Evason, Kristin Brown, Andrew Graham Cox
This study shows NRF2 drives liver cell plasticity by co-opting the SWI/SNF complex, and identifies FHD-286 as a therapeutic inhibitor of this process.
bioRxiv · Jun 2, 2026 · PreprintCancer Biology