Structural Lung Remodeling Precedes Functional Decline After Chronic Smoldering Douglas Fir Smoke Exposure in Apoe-/- Mice
Charbel Yazbeck, Jacqueline Matz, Matthew Eden, Shubham Rajput, Ye Chen, Michael J. Gollner, Paola Sebastiani B, Chiara Maria Bellini, Jessica M. Oakes
This study shows that structural and molecular lung damage occurs before functional decline in mice exposed to smoke, highlighting the need for early biomarkers in firefighters.
bioRxiv · May 29, 2026 · PreprintPhysiology