Jessica M. Oakes

Structural Lung Remodeling Precedes Functional Decline After Chronic Smoldering Douglas Fir Smoke Exposure in Apoe-/- Mice

This study shows that structural and molecular lung damage occurs before functional decline in mice exposed to smoke, highlighting the need for early biomarkers in firefighters.

Occupationally Relevant Wildfire Smoke Inhalation Impairs Nitric Oxide Signaling and Promotes Progressive Aortic Stiffening in Hypercholesterolemic Mice

This study shows that wildfire smoke exposure in hypercholesterolemic mice causes vascular inflammation, oxidative stress, and fibrosis, leading to aortic stiffening and hypertension.

Co-Therapy with S1P and Heparan Sulfate Derivatives to Restore Endothelial Glycocalyx and Combat Pro-Atherosclerotic Endothelial Dysfunction

This study evaluates a therapy combining S1P and heparin to restore endothelial glycocalyx in disturbed flow conditions and improve vascular function.