Building Blocks of Understanding: Constructing a Reverse Genetics Platform for studying determinants of SARS-CoV-2 replication.
Marco Olguin-Nava, Patrick Bohn, Thomas Hennig, Charlene Börtlein, Anne-Sophie Gribling-Burrer, Nora Schmidt, Neva Caliskan, Lars Dölken, Mathias Munschauer, Redmond P. Smyth
This paper develops a reverse genetics platform for SARS-CoV-2 to generate recombinant viruses and study their replication and phenotypic effects.
bioRxiv · Feb 5, 2024 · PreprintMicrobiology