Author

Charlie Sharp

Imperial College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alan ArmstrongiD· 1 shared Ariba Azam· 1 shared C. C. BrowniD· 1 shared David J. ManniD· 1 shared Elliot O Harmer· 1 shared James A. BulliD· 1 shared Sam HorrelliD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Alan ArmstrongORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Discovery of Covalent Wild-Type Isocitrate Dehydrogenase 1 (IDH1) Inhibitors Targeting Cys269

C. C. Brown, Elliot O Harmer, Ariba Azam, Charlie Sharp, Sam Horrell, James A. Bull, Alan Armstrong, David J. Mann

This study develops covalent inhibitors targeting wild-type IDH1 by exploiting a unique hydrogen bonding network, achieving high potency and selectivity.

bioRxiv · Sep 25, 2026 · PreprintCancer Biology