Author

Chase Alan Brown

Oklahoma Medical Research Foundation

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Assay:DNA methylation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Jonathan D. WreniD· 3 shared Cory B. GilesiD· 1 shared David R. StanfordiD· 1 shared Hunter L. PorteriD· 1 shared Mark M. HuyckeiD· 1 shared Ram Babu UndiiD· 1 shared Victor A. AnsereiD· 1 shared Walker HoolehaniD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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3 shared papersBioinformatics

Jonathan D. WrenORCID

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3 papers

Recent·Most cited

Methylation Array Signals are Predictive of Chronological Age Without Bisulfite Conversion

Hunter L. Porter, Victor A. Ansere, Ram Babu Undi, Walker Hoolehan, Cory B. Giles, Chase Alan Brown, David R. Stanford, Mark M. Huycke, Willard M. Freeman, Jonathan D. Wren

The paper shows that non-methylation factors cause age-predictive pseudomethylation signals in methylation arrays, affecting epigenetic clocks.

GeroScience · Jul 29, 2025Peer-reviewedMolecular Biology

AutoGDC: A Python Package for DNA Methylation and Transcription Meta-Analyses

Chase Alan Brown, Jonathan D. Wren

AutoGDC provides a Python package for streamlined DNA methylation and RNA sequencing meta-analyses using data from the Genomic Data Commons.

bioRxiv · Apr 14, 2024 · PreprintBioinformatics

Persistent homology centrality improves link prediction performance in PubMed co-occurrence networks

Chase Alan Brown, Jonathan D. Wren

This paper introduces a method using persistent homology to predict links in PubMed co-occurrence networks by analyzing the dynamic structure of scientific literature.

bioRxiv · Mar 19, 2024 · PreprintBioinformatics