The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth
Ionel Sandovici, Aikaterini Georgopoulou, Vicente Pérez-García, Antonia Hufnagel, Jorge López‐Tello, Brian Lam, Samira Schiefer, Chelsea Gaudreau, Fátima Santos, Katharina Hoelle, Giles S.H. Yeo, Keith Burling, Moritz Reiterer, Abigail L. Fowden, Graham J. Burton, , Miguel Constância
This study shows that the imprinted Igf2-Igf2r axis is essential for coordinating placental microvasculature expansion with fetal growth in mice.
Developmental Cell · Dec 27, 2021Peer-reviewedDevelopmental Biology