Author

Katharina Hoelle

NIHR Cambridge Biomedical Research Centre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Ionel SandoviciiD· 2 shared Miguel ConstânciaiD· 2 shared Abigail L. FowdeniD· 1 shared Aikaterini Georgopoulou· 1 shared Amanda Nancy Sferruzzi-PerriiD· 1 shared Anne E. WillisiD· 1 shared Antonia HufnageliD· 1 shared Brian LamiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersDevelopmental Biology

Ionel SandoviciORCID

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2 papers

Recent·Most cited

The imprinted Mir483 is a growth suppressor and metabolic regulator functioning through IGF1

Ionel Sandovici, Denise S. Fernandez‐Twinn, Niamh Campbell, Wendy N. Cooper, Yoichi Sekita, Ilona Zvetkova, David Ferland-McCollough, Haydn M. Prosser, Lila M. Oyama, Danilo Cimadomo, Karina Barbosa de Queiroz, Cecilia S. K. Cheuk, Nicola M. Smith, Richard G. Kay, Katharina Hoelle, , Miguel Constância

This study identifies Mir483 as a growth suppressor and metabolic regulator that antagonizes its host gene Igf2 through IGF1 signaling, revealing a novel mechanism of growth control.

bioRxiv · Sep 9, 2022 · PreprintDevelopmental Biology

The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth

Ionel Sandovici, Aikaterini Georgopoulou, Vicente Pérez-García, Antonia Hufnagel, Jorge López‐Tello, Brian Lam, Samira Schiefer, Chelsea Gaudreau, Fátima Santos, Katharina Hoelle, Giles S.H. Yeo, Keith Burling, Moritz Reiterer, Abigail L. Fowden, Graham J. Burton, , Miguel Constância

This study shows that the imprinted Igf2-Igf2r axis is essential for coordinating placental microvasculature expansion with fetal growth in mice.

Developmental Cell · Dec 27, 2021Peer-reviewedDevelopmental Biology