DNA-PK Promotes DNA End Resection at DNA Double Strand Breaks in G0 cells
Faith C. Fowler, Bo-Ruei Chen, Nicholas Zolnerowich, Wei Wu, Raphael Pavani, Jacob Paiano, Chelsea Peart, Zulong Chen, André Nussenzweig, Barry P. Sleckman, Jessica K. Tyler
The paper shows DNA-PK promotes DNA end resection in G0 cells but not in G1 or G2 phase cells, revealing a cell cycle-specific role in DSB repair.
eLife · May 9, 2022Peer-reviewedMolecular Biology