Author

Bo-Ruei Chen

University of Alabama at BirminghamORCID 0000-0001-6404-2099Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

André NussenzweigiD· 2 shared Barry P. SleckmaniD· 2 shared Jessica K. TyleriD· 2 shared Chelsea Peart· 1 shared Faith C. FowleriD· 1 shared Gabriel E. Matos-RodriguesiD· 1 shared Jacob PaianoiD· 1 shared Jason Romero NeidigkiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

André NussenzweigORCID

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2 papers

Recent·Most cited

Cell BiologyScience AdvancesPeer-reviewedJun 20, 2025

Senataxin and DNA-PKcs Redundantly Promote Non-Homologous End Joining Repair of DNA Double Strand Breaks During V(D)J Recombination

Bo-Ruei Chen, Thu N. Pham, Lance Dylan Reynolds…·Barry P. Sleckman

The paper shows senataxin and DNA-PKcs redundantly support NHEJ repair of RAG-induced DSBs during V(D)J recombination, with senataxin's function overlapping with RECQL5 and HLTF.

2 citations

mouseDNA methylation

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Molecular BiologyeLifePeer-reviewedMay 9, 2022

DNA-PK Promotes DNA End Resection at DNA Double Strand Breaks in G0 cells

Faith C. Fowler, Bo-Ruei Chen, Nicholas Zolnerowich…·Jessica K. Tyler

The paper shows DNA-PK promotes DNA end resection in G0 cells but not in G1 or G2 phase cells, revealing a cell cycle-specific role in DSB repair.

22 citations

humanexperimental assay

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