Core elements play distinct roles in promoter birth and transcriptional regulation
Syue-Ting Antony Kuo, Wei-Yi Shen, Shinn-Juh Lai, Joshua Kevin Chang, Cheng-Wei Ni, Chih-Chiang Chang, Zoltan Palmai, Lee-Wei Yang, Nei-Li Chan, I‐Ren Lee, Hsin-Hung David Chou
The paper investigates the roles of core promoter elements -35 and -10 in Escherichia coli, showing -10 is essential for promoter evolution while -35 influences gene regulation through interactions with transcription factors.
Nature Communications · Jul 17, 2026Peer-reviewedSystems Biology