Author

Wei-Yi Shen

National Taiwan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Hsin-Hung David ChouiD· 2 shared Joshua Kevin Chang· 2 shared Shinn-Juh LaiiD· 2 shared Syue-Ting Antony KuoiD· 2 shared Cheng-Wei Ni· 1 shared Chih-Chiang Chang· 1 shared Christine Hsu· 1 shared Clara Chang· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersSystems Biology

Hsin-Hung David ChouORCID

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2 papers

Recent·Most cited

Core elements play distinct roles in promoter birth and transcriptional regulation

Syue-Ting Antony Kuo, Wei-Yi Shen, Shinn-Juh Lai, Joshua Kevin Chang, Cheng-Wei Ni, Chih-Chiang Chang, Zoltan Palmai, Lee-Wei Yang, Nei-Li Chan, I‐Ren Lee, Hsin-Hung David Chou

The paper investigates the roles of core promoter elements -35 and -10 in Escherichia coli, showing -10 is essential for promoter evolution while -35 influences gene regulation through interactions with transcription factors.

Nature Communications · Jul 17, 2026Peer-reviewedSystems Biology

Unraveling the start element and regulatory divergence of core promoters across the domain Bacteria

Syue-Ting Antony Kuo, Joshua Kevin Chang, Clara Chang, Wei-Yi Shen, Christine Hsu, Shinn-Juh Lai, Hsin-Hung David Chou

The paper identifies a conserved 3-bp promoter element and reveals regulatory divergence in bacterial promoters between Terrabacteria and Gracilicutes.

Nucleic Acids Research · Nov 13, 2025Peer-reviewedGenomics