Pancreatic α and β cells are globally phase-locked
Huixia Ren, Yanjun Li, Chengsheng Han, Yi Yu, Bowen Shi, Xiaohong Peng, Tianming Zhang, Shufang Wu, Xiaojing Yang, Kim Sneppen, Liangyi Chen, Chao Tang
The paper shows that pancreatic α and β cells exhibit globally phase-locked Ca2+ oscillations with tunable phase shifts that set islet oscillation patterns.
Nature Communications · Jun 28, 2022Peer-reviewedSystems Biology