Xiaohong Peng

Cortex-wide single-cell activity mapping in freely moving mice

The paper introduces COMET, a lightweight head-mounted mesoscope for cortex-wide single-cell calcium imaging in freely moving mice, demonstrating its ability to capture neural activity during natural behaviors.

δ-α cell-to-cell interactions modulate pancreatic islet Ca2+ oscillation modes

The paper shows that δ-cell interactions modulate pancreatic islet Ca2+ oscillation patterns through somatostatin secretion and pharmacological/optogenetic perturbations, revealing a Hopf bifurcation mechanism.

Glycemia Shift Pancreatic Islets Rhythmicity via δ-α Cell in vivo, Impairment in Diabetes

This study shows that glycemia shifts induce a coordinated change in pancreatic islet Ca2+ oscillations, mediated by δ- and α-cells, which is impaired in diabetes.

Pancreatic α and β cells are globally phase-locked

The paper shows that pancreatic α and β cells exhibit globally phase-locked Ca2+ oscillations with tunable phase shifts that set islet oscillation patterns.