SENP1 in the retrosplenial agranular cortex regulates core autistic-like symptoms in mice
Kan Yang, Yuhan Shi, Xiujuan Du, Jincheng Wang, Yuefang Zhang, Shifang Shan, Yiting Yuan, Ruoqing Wang, Chenhuan Zhou, Yuting Liu, Zilin Cai, Yanzhi Wang, Liu Fan, Huatai Xu, Juehua Yu, , Zilong Qiu
This study identifies a SENP1 mutation in mice that causes core autistic-like symptoms by disrupting the SENP1-FMRP axis in the retrosplenial agranular cortex.
Cell Reports · Jan 1, 2021Peer-reviewedNeuroscience