Author

Chenjian Gu

Shanghai Medical College of Fudan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Ang LiiD· 1 shared Anthony J. BleyeriD· 1 shared Baolong ZhangiD· 1 shared Ben JiaiD· 1 shared Cancan CheniD· 1 shared Cheng LianiD· 1 shared Chuang Li· 1 shared Daoping RuiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Ang LiORCID

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2 papers

Recent·Most cited

MANF Clears Mutant Uromodulin in Human Kidney Organoids of Autosomal Dominant Tubulointerstitial Kidney Disease

Chenjian Gu, Yili Fang, Y. M. Wang, Eric Tycksen, Gayathri Kondepati, Chuang Li, Kendrah O. Kidd, Jun Liu, Fumihiko Urano, Maria Lindahl, Anthony J. Bleyer, Srikanth Singamaneni, Zhao Qing Sun, Ying Maggie Chen

This study shows MANF reduces mutant uromodulin in kidney organoids by enhancing autophagy through IP3R1 repression, suggesting potential for treating ADTKD and similar protein misfolding diseases.

Journal of Clinical Investigation · Aug 25, 2026Peer-reviewedGenetics

Human Identical Sequences of SARS-CoV-2 Promote Clinical Progression of COVID-19 by Upregulating Hyaluronan via NamiRNA-Enhancer Network

Wei Li, Shuai Yang, Peng Xu, Dapeng Zhang, Ying Tong, Lu Chen, Ben Jia, Ang Li, Cheng Lian, Daoping Ru, Baolong Zhang, Mengxing Liu, Cancan Chen, Weihui Fu, Songhua Yuan, , Wenqiang Yu

This paper identifies human identical sequences in SARS-CoV-2 that upregulate hyaluronan via a miRNA-enhancer network, contributing to cytokine storm and ARDS in COVID-19, suggesting potential therapeutic strategies.

EBioMedicine · Feb 1, 2022Peer-reviewedMolecular Biology