Srikanth Singamaneni

This study investigates hippocampal network dysfunction in a Wolfram syndrome mouse model, finding hyperexcitable neurons without seizures or increased network bursting.

This study shows MANF reduces mutant uromodulin in kidney organoids by enhancing autophagy through IP3R1 repression, suggesting potential for treating ADTKD and similar protein misfolding diseases.

This study shows that palmitoylation regulates mitochondrial transport of insulin across the endothelium, improving insulin sensitivity in insulin resistance.

This paper develops PEDOT:PSS granular hydrogel microparticles that form conducting hydrogels with microporosity and dynamic mechanical properties, enabling extrusion, bioencapsulation, and electrophysiological monitoring.