Author

Chenxin Wu

Tsinghua University

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Synthetic Biology· 1

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Approach:statistical model· 1

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Chuan ShaniD· 1 shared Jiong YuiD· 1 shared Lei Lu· 1 shared Xiaofang Zhong· 1 shared Yuan GaoiD· 1 shared Zhuoyun Ren· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperSynthetic Biology

Chuan ShanORCID

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1 paper

Recent·Most cited

De novo design of metalloenzymes using Metal Mer

Chuan Shan, Zhuoyun Ren, Jiong Yu, Yuan Gao, Chenxin Wu, Xiaofang Zhong, Lei Lu

This paper introduces a computational pipeline for de novo metalloenzyme design using Metal Mer, achieving high selectivity and activity in catalytic reactions without directed evolution.

bioRxiv · Oct 16, 2026 · PreprintSynthetic Biology