Author

Lei Lu

Center for Life SciencesPrimary ORCID profile (0000-0001-7097-1505 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Lei LuiD1 paper · University of California, San Francisco

Biology Disciplines

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Cell Biology· 1 Plant Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 2 Organism:Arabidopsis· 1 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Baoge Huang· 1 shared Chao WangiD· 1 shared Chenchen Hu· 1 shared Chenxin Wu· 1 shared Chuan ShaniD· 1 shared Gaojie WangiD· 1 shared Guanghao GuoiD· 1 shared Guangwei LiiD· 1 shared

Activity by Year

2016-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPlant Biology

Baoge Huang

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3 papers

Recent·Most cited

De novo design of metalloenzymes using Metal Mer

Chuan Shan, Zhuoyun Ren, Jiong Yu, Yuan Gao, Chenxin Wu, Xiaofang Zhong, Lei Lu

This paper introduces a computational pipeline for de novo metalloenzyme design using Metal Mer, achieving high selectivity and activity in catalytic reactions without directed evolution.

bioRxiv · Oct 16, 2026 · PreprintSynthetic Biology

An activated wheat CCG10-NLR immune receptor forms an octameric resistosome

Guanghao Guo, He Zhao, Kaihong Bai, Professor Jian Lu, Qiuhong Wu, Lei Lu, Yue Zhang, Lingli Dong, Guangwei Li, Yongxing Chen, Yikun Hou, Ping Lu, Miaomiao Li, Huaizhi Zhang, Gaojie Wang, , Jonathan D. G. Jones

Activated wheat CCG10-NLR immune receptor WAI3 and Arabidopsis RPS2 assemble into octameric calcium-permeable resistosomes with an inverted coiled-coil domain topology associated with lacking the conserved EDVID motif.

Cell · Mar 20, 2026Peer-reviewedPlant Biology✦ In-depth digest

The ciliary targeting of membrane proteins by a ternary complex comprising transportin1, Rab8 and the ciliary targeting signal

Viswanadh Madugula, Lei Lu

The paper identifies a ternary complex of TNPO1, Rab8, and CTS that mediates selective entry and retention of ciliary membrane proteins.

bioRxiv · Jun 17, 2016Cell Biology