Guillermo González‐Burgos

The paper identifies reduced SST mRNA and depletion of specific upper-layer Sst interneurons in schizophrenia using single-nucleus RNA-seq and spatial transcriptomics.

The paper compares distractibility between marmosets and macaques in cognitive tasks and links it to dopamine D1 receptor expression in prefrontal parvalbumin neurons.

This paper introduces SISTM to map 3D synaptic nanoarchitecture in brain tissue across species using cryo-ET and STA, revealing conserved structural features in human postmortem tissue.

The paper investigates how intrinsic spike frequency adaptation (I-SFA) and inhibitory circuit dynamics contribute to extrinsic-SFA (E-SFA) in primate lateral prefrontal cortex neurons during behavior.

This study reduces neuronal excitability in monkey prefrontal cortex using Kir2.1 channels and finds decreased excitatory synaptic strength without affecting inhibitory inputs.

The paper examines single neuron diversity in primate visual cortical areas V1 and LPFC, finding differences in morphology, electrophysiology, and intrinsic bursting that may underlie functional specialization.

This study shows that kynurenic acid (KYNA) and its enzyme KAT II expand in primate dlPFC, impairing cognitive functions by affecting NMDA and nic-7Rs, and suggests targeting KYNA as a therapeutic approach for neuroinflammatory disorders.

The paper quantifies microglial contamination in Patch-seq datasets and shows its impact on electrophysiological properties of neurons.

The paper investigates why gamma oscillations have higher frequency in primate prefrontal cortex compared to parietal cortex, finding no differences in GABAAR inhibition but suggesting stronger excitatory drive in prefrontal neurons.

This study investigates the role of Kcns3 in PV neuron function using computational models and electrophysiology in Kcns3-deficient mice, finding disruptions in firing patterns and gamma oscillations.

This study compares layer 3 pyramidal neurons in monkey prefrontal and parietal cortex, finding differences in physiology, morphology, and gene expression between the regions.