Beyond Histology: A Validated CUBIC-Based Workflow for Volumetric Analysis of Follicles and Cortical Vasculature in Human Ovarian Tissue
Despina I. Pavlidis, Chloe E Fischer, Maria A Jennings, Jordan H. Machlin, Victoria Jan, Brendon M. Baker, Ariella Shikanov
This paper validates a CUBIC-based workflow for volumetric analysis of follicles and vasculature in human ovarian tissue, showing comparable follicle density to histology and detailed vascular morphometrics.
bioRxiv · Apr 21, 2026 · PreprintBioengineering