Jordan H. Machlin

This paper validates a CUBIC-based workflow for volumetric analysis of follicles and vasculature in human ovarian tissue, showing comparable follicle density to histology and detailed vascular morphometrics.

This study shows that encapsulated human ovarian xenografts restore endocrine function in ovariectomized mice, integrating with the host's hypothalamus-pituitary-gonad axis and maintaining cyclicity and hormone levels.

This study examines the transcriptomic and proteomic changes in cultured ovarian follicles, identifying gene expression patterns and differentially expressed genes between group culture conditions.

The paper analyzes single-oocyte RNA sequencing data from early-stage human follicles to identify differentially expressed genes between primordial and transitioning stages.

This study uses scRNA-seq to identify cellular heterogeneity in human fallopian tubes, revealing distinct cell types and changes in disease states.