Author

Despina I. Pavlidis

University of MichiganORCID 0000-0002-2156-3561Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Ariella ShikanoviD· 5 shared Brendon M. BakeriD· 4 shared Chloe E Fischer· 2 shared Delaney S Sinko· 2 shared Margaret A. BrunetteiD· 2 shared Monica A. RiondaiD· 2 shared Sasha Cai Lesher‐PéreziD· 2 shared Vasantha PadmanabhaniD· 2 shared

Activity by Year

2025-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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5 shared papersBioengineering

Ariella ShikanovORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Filling the Void: Rapid Revascularization via Vasculogenic Assembly in Semi-synthetic Granular Hydrogel Grafts

Michael M. Hu, Despina I. Pavlidis, Courtney M. Lestock, Gonzalo Anyosa-Galvez, Kaley Lollis, Yimeng Zhao, Firaol S. Midekssa, Robert Kent, Ariella Shikanov, Brendon M. Baker

This study develops granular hydrogel composites (GHCs) that enable rapid revascularization of tissue grafts by promoting vascular network formation and integration with host vasculature.

bioRxiv · Jun 16, 2026 · PreprintBioengineering

A robust and user-agnostic step-emulsion platform for scalable microgel fabrication

Durante Pioche-Lee, Shiyu Yang, Xiaoqian Wang, Yoke Qi Ho, Wahidur Rahman, Armen C Vartanian, Despina I. Pavlidis, Irene W. Zhang, Julia E. Vallier, Emily McCorkle, Andrew Schaefer, Andrew J. Putnam, Ariella Shikanov, Cole A. DeForest, Sasha Cai Lesher‐Pérez

This paper introduces a step-emulsion platform for scalable microgel fabrication that is robust, user-agnostic, and compatible with various materials and viscosities.

bioRxiv · May 21, 2026 · PreprintBioengineering

Microporous Immune-Isolating Capsule with Improved Diffusion for Restored Dynamic Bidirectional Hormone Signaling in a Murine Model of Premature Ovarian Insufficiency

Delaney S Sinko, Margaret A. Brunette, Despina I. Pavlidis, Monica A. Rionda, Bipasha Ray, Michelle Tong, Suhani Thakur, Brendon M. Baker, Vasantha Padmanabhan, Ariella Shikanov

This paper develops microporous immune-isolating capsules that restore dynamic hormone signaling in a mouse model of premature ovarian insufficiency by enabling size-selective diffusion of hormones.

bioRxiv · May 1, 2026 · PreprintBioengineering

Beyond Histology: A Validated CUBIC-Based Workflow for Volumetric Analysis of Follicles and Cortical Vasculature in Human Ovarian Tissue

Despina I. Pavlidis, Chloe E Fischer, Maria A Jennings, Jordan H. Machlin, Victoria Jan, Brendon M. Baker, Ariella Shikanov

This paper validates a CUBIC-based workflow for volumetric analysis of follicles and vasculature in human ovarian tissue, showing comparable follicle density to histology and detailed vascular morphometrics.

bioRxiv · Apr 21, 2026 · PreprintBioengineering

MAP hydrogel promotes revascularization of human ovarian graft and integration with the hypothalamic-pituitary axis in a mouse model of primary ovarian insufficiency

Despina I. Pavlidis, Monica A. Rionda, Chloe E Fischer, Maria A. Jennings, Delaney S Sinko, Bhavya Vats, Margaret A. Brunette, Sasha Cai Lesher‐Pérez, Vasantha Padmanabhan, Brendon M. Baker, Ariella Shikanov

This study shows that MAP hydrogel encapsulation improves revascularization and endocrine function of transplanted ovarian tissue in a mouse model of primary ovarian insufficiency.

bioRxiv · Dec 11, 2025 · PreprintBioengineering