Glycolytic inhibitor 2-deoxyglucose prevents cortical hyperexcitability after traumatic brain injury
Jenny B. Koenig, David Cantu, Cho Low, Mary Sommer, Farzad Noubary, Danielle Croker, Michael J. Whalen, Dong Kong, Chris G. Dulla
In vivo treatment with 2-deoxyglucose after traumatic brain injury in mice prevented cortical hyperexcitability, synaptic changes, and loss of GABAergic interneurons.
JCI Insight · Apr 30, 2019Peer-reviewedNeuroscience