Author

Chong Chen

Sichuan UniversityORCID 0000-0002-6787-0495Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

CHONG CHEN6 papers · Harvard University

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Banglei Yin· 1 shared Bing HuiD· 1 shared Chaoxin XiaoiD· 1 shared Chengjian ZhaoiD· 1 shared Chun-Wei George WuiD· 1 shared Dai Xie· 1 shared Dan CaoiD· 1 shared Dunfang ZhangiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Banglei Yin

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3 papers

Recent·Most cited

A Novel 3D Visualization Method in Mice Identifies the Periportal Lamellar Complex (PLC) as a Key Regulator of Hepatic Ductal and Neuronal Branching Morphogenesis

Tongtong Xu, Fujun Cao, Ruihan Zhou, Qin Chen, Jian Zhong, Yulin Wang, Chaoxin Xiao, Banglei Yin, Chong Chen, Chengjian Zhao

The paper develops a 3D imaging method to identify the Periportal Lamellar Complex (PLC) as a structural regulator of liver ductal and neuronal branching.

eLife · Apr 22, 2026Peer-reviewedCell Biology

Genome-wide mapping of native co-localized G4s and R-loops in living cells

Ting Liu, Xing Shen, Yijia Ren, Hongyu Lu, Yu Liu, Chong Chen, Lin Yu, Zhihong Xue

The paper develops methods to map native co-localized G4s and R-loops in living cells and shows their role in transcriptional regulation.

eLife · Oct 11, 2024Peer-reviewedGenomics

Nuclear stiffening in neoplastic cells aggregates T cell exhaustion via pFAK/SP1/IL-6 axis in colorectal cancer

Hao Kong, Xiangji Wu, Qingxin Yang, Qian Sun, Xin Yu, Yu Dai, Chun-Wei George Wu, Dai Xie, Lang Chen, Panpan Ma, Siqi Dai, Chong Chen, Peng Mi, Xiaodong Feng, Yong Li Peng, , Hong Jiang

The paper shows that nuclear stiffening in colorectal cancer cells promotes T cell exhaustion through the pFAK/SP1/IL-6 axis, and inhibiting pFAK improves antitumor immunity.

bioRxiv · Jul 24, 2024 · PreprintImmunology