Adrien Tassou

This study maps the development of sensory and sympathetic innervation in the kidney, identifying key nerve types and their origins.

The paper identifies distinct transcriptional responses in microglia during opioid exposure and neuropathic pain, highlighting injury-specific mechanisms and the absence of opioid-induced transcriptional changes.

The paper uses graph theory to analyze the structural pain network, revealing it is assortative and vulnerable to attacks on hub nodes.

This study shows that inhibiting FLT3 signaling preserves opioid analgesia while preventing tolerance and hyperalgesia in chronic pain models.

The paper maps opioid receptor expression across brainstem circuits and identifies functional implications in respiratory and sensory pathways.

This study shows that repeated peripheral nerve injury promotes exaggerated pain and mood disorders, which are linked to spinal microglial activation, and that FLT3 inhibition can prevent these effects.

This study shows that dopamine D2 receptors in the extended amygdala are crucial for switching between passive and active defensive behaviors in response to threats.