Modelling dementia in Drosophila uncovers shared and specific targets of TDP-43 proteinopathy across ALS and FTD relevant circuits
Rebekah Keating Godfrey, Reed T. Bjork, Eric B. Alsop, Brijesh Singh Chauhan, Hillary C. Ruvalcaba, Jerry Antone, Allison F. Michael, Christi Williams, Grace Hala’ufia, Alexander D. Blythe, Megan C. Hall, Kendall R. Van Keuren‐Jensen, Daniela C. Zarnescu
This study uses a Drosophila model to investigate TDP-43 proteinopathy in ALS and FTD, identifying shared and circuit-specific molecular targets.
bioRxiv · Nov 16, 2022 · PreprintNeuroscience