Thyroid Hormone Suppresses Medulloblastoma Progression Through Promoting Terminal Differentiation of Tumor Cells
Yijun Yang, Silvia Anahi Valdés-Rives, Qing Liu, Tong Gao, Chakkapong Burudpakdee, Yuzhe Li, Jun Tan, Yinfei Tan, Christian A. Koch, Yuan Rong, Steven R. Houser, Shuanzeng Wei, Kathy Qi Cai, Jinhua Wu, Sheue-yann Cheng, , Zeng-jie Yang
This study shows thyroid hormone promotes differentiation of medulloblastoma cells, reducing tumor growth by reversing EZH2-mediated repression of NeuroD1.
Cancer Cell · Aug 1, 2024Peer-reviewedCancer Biology