A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer’s disease brain
Ebru Ercan-Herbst, Jens Ehrig, David C. Schöndorf, Annika Behrendt, Bernd Klaus, Borja Gomez Ramos, Nuria Prat Oriol, Christian Weber, Dagmar E. Ehrnhoefer
The paper identifies specific phosphorylation sites on soluble tau oligomers in early Alzheimer’s disease that differ from those in neurofibrillary tangles.
Acta Neuropathologica Communications · Dec 1, 2019Peer-reviewedNeuroscience