Author

Christine Jenny

Genethon (France)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anaïs BrassieriD· 2 shared Jérémie CosetteiD· 2 shared Julie Oustelandt· 2 shared Marine LaurentiD· 2 shared Mario AmendolaiD· 2 shared Rim Harb· 2 shared Aristide Ferrante· 1 shared Cláudia PiccoliiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Anaïs BrassierORCID

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2 papers

Recent·Most cited

Rescue of lysosomal acid lipase deficiency in mice by rAAV8 liver gene transfer.

Marine Laurent, Rim Harb, Christine Jenny, Julie Oustelandt, Simon Jimenez, Jérémie Cosette, Francesca Landini, Aristide Ferrante, Guillaume Corre, Nemanja Vujić, Cláudia Piccoli, Anaïs Brassier, Laetitia van Wittenberghe, Giuseppe Ronzitti, Dagmar Kratky, , Mario Amendola

The paper develops a liver-targeted gene therapy using recombinant AAV8 to cure Lysosomal acid lipase deficiency by correcting lipid accumulation and normalizing gene expression and mitochondrial function in a mouse model.

Communications Medicine · Apr 11, 2025Peer-reviewedMolecular Biology

Novel cytometry-based characterization of lysosomal storage disease affected patient's cells

Marine Laurent, Jérémie Cosette, Giulia Pavani, Sarah BAYOL, Christine Jenny, Rim Harb, Julie Oustelandt, Anaïs Brassier, Daniel Stockholm, Mario Amendola

This paper characterizes lysosomal storage disease using imaging and cytometry to assess lipid homeostasis in patient cells and validates findings in alternative models.

bioRxiv · Mar 18, 2025 · PreprintPathology