Author

Julie Oustelandt

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Pathology· 1

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Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Marine LaurentiD· 3 shared Mario AmendolaiD· 3 shared Anaïs BrassieriD· 2 shared Christine Jenny· 2 shared Giulia PavaniiD· 2 shared Guillaume CorreiD· 2 shared Jérémie CosetteiD· 2 shared Rim Harb· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMolecular Biology

Marine LaurentORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CRISPR-Mediated Linearization of IDLV Donor Enables Precise Targeted Integration in Human Hematopoietic Stem Cells

Giulia Scalisi, Aboud Sakkal, Laurie Lacombe, Francesco Sarnari, Marine Rouillon, Michela Rosiello, Alexandra Tachtsidi, Paola Galbiati, Guillaume Corre, Julie Oustelandt, Giulia Pavani, Marine Laurent, Mike A. Firth, Marie As, Marcello Maresca, , Mario Amendola

This paper introduces TILV, a CRISPR-assisted method for precise targeted integration of transgenes in human hematopoietic stem cells using IDLV donors, showing improved efficiency and minimal impact on cell viability.

bioRxiv · Jun 17, 2026 · PreprintMolecular Biology

Rescue of lysosomal acid lipase deficiency in mice by rAAV8 liver gene transfer.

Marine Laurent, Rim Harb, Christine Jenny, Julie Oustelandt, Simon Jimenez, Jérémie Cosette, Francesca Landini, Aristide Ferrante, Guillaume Corre, Nemanja Vujić, Cláudia Piccoli, Anaïs Brassier, Laetitia van Wittenberghe, Giuseppe Ronzitti, Dagmar Kratky, , Mario Amendola

The paper develops a liver-targeted gene therapy using recombinant AAV8 to cure Lysosomal acid lipase deficiency by correcting lipid accumulation and normalizing gene expression and mitochondrial function in a mouse model.

Communications Medicine · Apr 11, 2025Peer-reviewedMolecular Biology

Novel cytometry-based characterization of lysosomal storage disease affected patient's cells

Marine Laurent, Jérémie Cosette, Giulia Pavani, Sarah BAYOL, Christine Jenny, Rim Harb, Julie Oustelandt, Anaïs Brassier, Daniel Stockholm, Mario Amendola

This paper characterizes lysosomal storage disease using imaging and cytometry to assess lipid homeostasis in patient cells and validates findings in alternative models.

bioRxiv · Mar 18, 2025 · PreprintPathology