Author

Simon Jimenez

Genethon (France)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Anaïs BrassieriD· 1 shared Aristide Ferrante· 1 shared Christine Jenny· 1 shared Cláudia PiccoliiD· 1 shared Consiglia PacelliiD· 1 shared Dagmar KratkyiD· 1 shared Francesca Landini· 1 shared Giuseppe RonzittiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Anaïs BrassierORCID

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Author profile →

1 paper

Recent·Most cited

Rescue of lysosomal acid lipase deficiency in mice by rAAV8 liver gene transfer.

Marine Laurent, Rim Harb, Christine Jenny, Julie Oustelandt, Simon Jimenez, Jérémie Cosette, Francesca Landini, Aristide Ferrante, Guillaume Corre, Nemanja Vujić, Cláudia Piccoli, Anaïs Brassier, Laetitia van Wittenberghe, Giuseppe Ronzitti, Dagmar Kratky, , Mario Amendola

The paper develops a liver-targeted gene therapy using recombinant AAV8 to cure Lysosomal acid lipase deficiency by correcting lipid accumulation and normalizing gene expression and mitochondrial function in a mouse model.

Communications Medicine · Apr 11, 2025Peer-reviewedMolecular Biology