Developmental factors drive the compartmentalised and discontinuous maturation of the small intestinal epithelium during the early postnatal period
Johannes Schöneich, Aline Dupont, Stefan Schlößer, Matthias A. Schmitz, Isabel Richter, Narasimha Murthy Keshava Prasad Gubbi, Mingbo Cheng, Tiago Maié, Sofia Jäverfelt, Fabian Imdahl, Christophe Toussaint, Antoine-Emmanuel Saliba, Christoph Kuppe, Thaher Pelaseyed, Ivan G. Costa, Mathias W. Hornef
This study investigates the postnatal maturation of the small intestinal epithelium, identifying developmental regulators as key drivers over microbiota effects.
bioRxiv · May 15, 2025 · PreprintImmunology