Mathias Walter Hornef

This study shows that bacterial LPS binds RETREG1 to induce ER remodeling and enhance antibacterial defense through ERphagy.

The paper identifies a neonatal liver program that expands regulatory T cells while limiting conventional T cell activation, influencing susceptibility to viral infections and protection against liver disease.

This study investigates the postnatal maturation of the small intestinal epithelium, identifying developmental regulators as key drivers over microbiota effects.

The paper identifies RORγt-expressing dendritic cells as a distinct APC lineage conserved across tissues and species, with functions beyond promoting tolerance.

This study shows that Salmonella SopB suppresses mucosal inflammation and disease progression in a phosphatase-independent manner during infection.

This study develops a physiologically-based model of bile acid metabolism in mice to understand its dynamics and implications for disease.