Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms
Christopher Bell, Lukas Kilo, Daniel Gottschalk, Jashar Arian, Lea Deneke, Hanna B. Kern, Christof Rickert, Oliver Kobler, Julia Strauß, Martin Heine, Carsten Duch, Stefanie Ryglewski
This study shows that alternative splicing of the Drosophila Cav2 gene regulates distinct presynaptic functions, with different splice variants affecting synaptic vesicle release and short-term plasticity.
eLife · Feb 14, 2025Peer-reviewedNeuroscience