Author

Lukas Kilo

RWTH Aachen UniversityORCID 0000-0002-2787-044XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Assay:electronic health records· 1

Frequent Co-Authors

Aaron VoigtiD· 1 shared Aileen Wechner· 1 shared Carsten DuchiD· 1 shared Christof RickertiD· 1 shared Christopher Bell· 1 shared Daniel Gottschalk· 1 shared Florian P. FischeriD· 1 shared Gaia TavosanisiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Aaron VoigtORCID

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2 papers

Recent·Most cited

Modeling AP2M1 Developmental and Epileptic Encephalopathy in Drosophila

Robin A. Karge, Florian P. Fischer, Hannah Schüth, Aileen Wechner, Sabrina Peter, Lukas Kilo, Mato Dichter, Aaron Voigt, Gaia Tavosanis, Karen M. J. van Loo, Henner Koch, Yvonne G. Weber, Stefan Wolking

This study models AP2M1-DEE in Drosophila, finding heat-sensitive paralysis, altered neuron morphology, and seizure resistance, suggesting developmental defects over synaptic dysfunction.

Disease Models & Mechanisms · Sep 29, 2025Peer-reviewedNeuroscience

Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms

Christopher Bell, Lukas Kilo, Daniel Gottschalk, Jashar Arian, Lea Deneke, Hanna B. Kern, Christof Rickert, Oliver Kobler, Julia Strauß, Martin Heine, Carsten Duch, Stefanie Ryglewski

This study shows that alternative splicing of the Drosophila Cav2 gene regulates distinct presynaptic functions, with different splice variants affecting synaptic vesicle release and short-term plasticity.

eLife · Feb 14, 2025Peer-reviewedNeuroscience