Author

Christopher D. Thompton

Manchester Metropolitan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Ángeles AlmeidaiD· 1 shared Aseel M. SharairehiD· 1 shared Brenda Morant-FerrandoiD· 1 shared Carlos Vicente‐GutiérreziD· 1 shared Costantina Buondelmonte· 1 shared Daniel Jiménez-BlascoiD· 1 shared Diego Luis MedinaiD· 1 shared Emilio FernándeziD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Ángeles AlmeidaORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Mitochondrial collapse links PFKFB3-promoted glycolysis with CLN7/MFSD8 neuronal ceroid lipofuscinosis pathogenesis

Irene López-Fabuel, Marina García Macia, Costantina Buondelmonte, Olga Burmistrova, Nicoló Bonora, Brenda Morant-Ferrando, Paula Alonso-Batan, Carlos Vicente‐Gutiérrez, Daniel Jiménez-Blasco, Rubén Quintana–Cabrera, Emilio Fernández, Aseel M. Sharaireh, Marta Guevara‐Ferrer, Lorna M. FitzPatrick, Christopher D. Thompton, , Juan Pedro Bolaños

This study identifies a metabolic shift driven by PFKFB3 in CLN7 disease, showing that targeting glycolysis can alleviate disease hallmarks in a mouse model and patient-derived cells.

bioRxiv · Oct 20, 2020 · PreprintNeuroscience