The master energy homeostasis regulator PGC-1alpha couples transcriptional co-activation and mRNA nuclear export
Simeon R. Mihaylov, Lydia M. Castelli, Ya-Hui Lin, Aytaç Gül, Nikita Soni, Christopher Hastings, Helen R. Flynn, Oana Păun, Mark J. Dickman, Ambrosius P. Snijders, Robert J. Goldstone, Oliver Bandmann, Tatyana A. Shelkovnikova, Heather Mortiboys, Sila K. Ultanir, Guillaume M. Hautbergue
This study identifies a novel RNA-binding function of PGC-1alpha that couples transcriptional co-activation with mRNA nuclear export and mitochondrial homeostasis.
Nature Communications · Sep 7, 2023Peer-reviewedMolecular Biology