Cyclic di-GMP as an Antitoxin Regulates Bacterial Genome Stability and Antibiotic Persistence in Biofilms
Hebin Liao, Xiaodan Yan, Chenyi Wang, Chun Huang, Wei Zhang, Leyi Xiao, Jun Jiang, Yongjia Bao, Tao Huang, Han‐Bo Zhang, Chunming Guo, Yufeng Zhang, Yingying Pu
The paper identifies a toxin-antitoxin system in biofilms where c-di-GMP regulates genome stability and antibiotic persistence by controlling HipH activity.
eLife · Aug 6, 2024Peer-reviewedMicrobiology