Yingying Pu

Dormant Bacteria's Fatal Attraction to RNA Bacteriophages

The paper shows RNA phages are eliminated in dormant bacteria via ROS-mediated damage, but survival depends on genomic redundancy through co-infection.

Aggresomes protect mRNA under stress in Escherichia coli

The paper shows that aggresomes in E. coli store mRNA under stress, aiding rapid recovery by protecting mRNA from degradation and facilitating translation reactivation.

Cyclic di-GMP as an Antitoxin Regulates Bacterial Genome Stability and Antibiotic Persistence in Biofilms

The paper identifies a toxin-antitoxin system in biofilms where c-di-GMP regulates genome stability and antibiotic persistence by controlling HipH activity.

Intra-genomic genes-to-genes correlation enables genome representation

The paper shows that combinations of highly variable core genes can accurately predict sequence variants and antibiotic resistance in bacterial genomes.