Comparison of extracellular vesicles and mechanically induced vesicles for structure determination of membrane proteins
Chunyang Wang, Ole Østergaard, Roberto Melero, Gabriela Nagy‐Davidescu, Matthias Eibauer, Jesper Velgaard Olsen, J.M. Carazo, Andreas Plückthun, Ohad Medalia
This study compares extracellular vesicles (EVs) and mechanically induced vesicles (MVs) for membrane protein structure determination, finding that MVs provide better structural representation of HER2 in native environments.
bioRxiv · Mar 6, 2026 · PreprintBiochemistry