Gabriela Nagy‐Davidescu

The paper presents the first X-ray structure of an NtA-mediated asymmetric BRAF dimer bound to MEK1, showing it is a catalytically active state, not an intermediate in BRAF activation.

This study compares extracellular vesicles (EVs) and mechanically induced vesicles (MVs) for membrane protein structure determination, finding that MVs provide better structural representation of HER2 in native environments.

The paper proposes an atomistic structural model of a Ras-Raf signalosome based on molecular dynamics simulations, mutagenesis, electron microscopy, and cell-based experiments.