Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infections.
Joshua Osowicki, Hannah R. C. Frost, Kristy I. Azzopardi, Alana L. Whitcombe, Reuben McGregor, Lauren H. Carlton, Ciara Baker, Loraine Fabri, Manisha Pandey, Michael F. Good, Jonathan Rhys Carapetis, Mark J. Walker, Pierre Robert Smeesters, Paul Vincent Licciardi, Nicole J. Moreland, , Andrew C. Steer
The paper examines antibody responses to S. pyogenes antigens in individuals with and without pharyngitis, finding differences in IgG and IgA levels and correlations with prior immunity.
Nature Communications · Dec 3, 2024Peer-reviewedImmunology