STK19 drives Transcription-Coupled Repair by stimulating repair complex stability, Pol II ubiquitylation and TFIIH recruitment
Anisha R. Ramadhin, Shun-Hsiao Lee, Di Zhou, Anita P. T. Salmazo, Camila Gonzalo-Hansen, Marjolein van Sluis, Cindy M.A. Blom, Roel C. Janssens, Anja Raams, Dick H. W. Dekkers, Karel Bezstarosti, Dea Slade, Wim Vermeulen, Alex Pines, Jeroen Demmers, , Jurgen A. F. Marteijn
This study identifies STK19 as a critical factor in transcription-coupled nucleotide excision repair by stabilizing the repair complex and promoting Pol II ubiquitylation and TFIIH recruitment.
bioRxiv · Jul 22, 2024 · PreprintMolecular Biology