Carrie Bernecky

The paper reports the structure of cytoplasmic RNA polymerase II and reveals how factors like Gdown1 and RPAP2 prevent premature transcription factor association during its biogenesis.

This study identifies Annexin A2 as a critical mediator of RIG-I-like receptor responses to viral infection by promoting MDA5 oligomerization and enhancing interferon production.

This study identifies STK19 as a critical factor in transcription-coupled nucleotide excision repair by stabilizing the repair complex and promoting Pol II ubiquitylation and TFIIH recruitment.