Molecular and functional dissection of the AP2-I/BDP1 transcriptional complex of the malaria parasite reveals a role beyond the red blood cell stages
Marine Le Berre, Lucille Mellottee, Anagha Rajesh Salvi, Pauline Touarin, Sylvie Auxilien, Virginie Ropars, Marie Chaptal, Cindy Ramiole, Abhinay Ramaprasad, Sylvie Nessler, Joana Santos
This study identifies the AP2-I/BDP1 transcriptional complex in malaria parasites, showing its role in blood stage development and sexual commitment, with potential as a drug target.
bioRxiv · Nov 26, 2025 · PreprintMicrobiology