Author

Sylvie Auxilien

Centre National de la Recherche ScientifiqueORCID 0000-0002-2002-1162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Abhinay RamaprasadiD· 1 shared Adeline Humbert· 1 shared Ana‐Andreea ArteniiD· 1 shared Anagha Rajesh Salvi· 1 shared Arianna Tisba· 1 shared Bruno CollinetiD· 1 shared Carlos A. H. FernandesiD· 1 shared Catherine Vénien‐BryaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperMicrobiology

Abhinay RamaprasadORCID

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3 papers

Recent·Most cited

Structure of the human KEOPS/tRNA complex and characterization of pathogenic variants responsible for the Galloway Mowat syndrome.

Charles Cirio, Sylvie Auxilien, Dominique Liger, Carlos A. H. Fernandes, Raoudha Dammak, Sophia Missoury, Emilie Zélie, Marion Dos Santos Malhao, Ana‐Andreea Arteni, David Touboul, Christelle Arrondel, Corinne Antignac, Géraldine Mollet, Catherine Vénien‐Bryan, Herman VAN TILBEURGH, Bruno Collinet

The paper determines the structure of the human KEOPS/tRNA complex and characterizes pathogenic variants in the t6A pathway linked to Galloway-Mowat syndrome.

bioRxiv · Mar 3, 2026 · PreprintBiochemistry

Molecular and functional dissection of the AP2-I/BDP1 transcriptional complex of the malaria parasite reveals a role beyond the red blood cell stages

Marine Le Berre, Lucille Mellottee, Anagha Rajesh Salvi, Pauline Touarin, Sylvie Auxilien, Virginie Ropars, Marie Chaptal, Cindy Ramiole, Abhinay Ramaprasad, Sylvie Nessler, Joana Santos

This study identifies the AP2-I/BDP1 transcriptional complex in malaria parasites, showing its role in blood stage development and sexual commitment, with potential as a drug target.

bioRxiv · Nov 26, 2025 · PreprintMicrobiology

Deciphering the RNA-based regulation mechanism of the phage-encoded AbiF system in Clostridioides difficile

Marion Saunier, Adeline Humbert, Victor Kreis, Peltier Johann, Arianna Tisba, Sylvie Auxilien, Marion Blum, Isabelle Caldelari, Jean‐François Lucier, Joe Ueda, Daniel Gautheret, Claire Toffano‐Nioche, Jessica Andréani, Louis‐Charles Fortier, Olga A. Soutourina

The paper identifies a new AbiF-like system in C. difficile and shows its regulation by a non-coding RNA through RNA-protein interactions.

bioRxiv · Apr 15, 2025 · PreprintMicrobiology