Lucille Mellottee

Molecular and functional dissection of the AP2-I/BDP1 transcriptional complex of the malaria parasite reveals a role beyond the red blood cell stages

This study identifies the AP2-I/BDP1 transcriptional complex in malaria parasites, showing its role in blood stage development and sexual commitment, with potential as a drug target.

Single cell RNA-sequencing identifies the gene expression profile of the asexual and sexual invasive merozoites of the human malaria parasite

This study uses scRNA-seq to identify gene expression profiles of asexual and sexual merozoites in Plasmodium falciparum, revealing key genes involved in invasion and sexual commitment.

jouvence, a new small nucleolar RNA required in the gut extends lifespan in Drosophila

This paper identifies a new Drosophila snoRNA, jouvence, that extends lifespan when overexpressed and reduces it when lost, suggesting a role in transcriptional control and evolutionary conservation.