A regulatory TRIF/IL-1R1 axis controls T-dependent IgA production in the intestines
Chi-Chang Sung, Nimat Gafar Badmus, Michelle Shao, Christhalia Jusuf, Claire Tang, Nathalie Groot, Shin‐Heng Chiou, Steven S An, Arnold B. Rabson, Qi Yang, Gaëtan Barbet
This study identifies TRIF and IL-1R1 as regulators of intestinal IgA production, showing their roles in controlling IgA class-switching and germinal center B cell differentiation.
bioRxiv · May 26, 2026 · PreprintImmunology