Author

Shin‐Heng Chiou

Rutgers, The State University of New JerseyORCID 0000-0001-9754-7712Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alexander KleyiD· 1 shared Arnold B. RabsoniD· 1 shared Arthur Roberts· 1 shared Chi-Chang SungiD· 1 shared Christhalia Jusuf· 1 shared Claire Tang· 1 shared Cristina MontagnaiD· 1 shared Emmanuel Zachariah· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

Alexander KleyORCID

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2 papers

Recent·Most cited

Hypoxia-induced metastatic heterogeneity in pancreatic cancer

Pradeep Moon Gunasekaran, Qianqian Wang, Polina Guseva, Yoke‐Chen Chang, Rajika Chauhan, Alexander Kley, Mengdie Xu, Gene Lee, Gregory Marshall, Siddharth Ghosh Roy, Yousef Masoudpoor, Oscar Li, Arthur Roberts, Kelly Watkins Walton, Lucyann Franciosa, , Shin‐Heng Chiou

This study shows hypoxia promotes metastasis in pancreatic cancer by suppressing Kdm8, leading to epigenetic and transcriptomic changes, increased chromosomal instability, and metastatic disease.

Nature Communications · Jul 30, 2026Peer-reviewedCell Biology

A regulatory TRIF/IL-1R1 axis controls T-dependent IgA production in the intestines

Chi-Chang Sung, Nimat Gafar Badmus, Michelle Shao, Christhalia Jusuf, Claire Tang, Nathalie Groot, Shin‐Heng Chiou, Steven S An, Arnold B. Rabson, Qi Yang, Gaëtan Barbet

This study identifies TRIF and IL-1R1 as regulators of intestinal IgA production, showing their roles in controlling IgA class-switching and germinal center B cell differentiation.

bioRxiv · May 26, 2026 · PreprintImmunology